FTY720-Mitoxy

FTY720-Mitoxy is a fingolimod hydrochloride (HY-12005) derivative with neuroprotective and PP2A activating activities. FTY720-Mitoxy has the property of targeting mitochondria. In addition, FTY720-Mitoxy protects neurons by reducing inflammatory responses and is used in the study of neurodegenerative diseases such as Parkinson's disease[1].

Product Specifications

CAS Number

[1604816-11-6]

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fty720-mitoxy.html

Smiles

O=C(NC(CO)(CO)CCC1=CC=C(CCCCCCCC)C=C1)CC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.[Br-]

Molecular Formula

C40H51BrNO3P

Molecular Weight

704.72

References & Citations

[1]Vargas-Medrano J, et al. Novel FTY720-based compounds stimulate neurotrophin expression and phosphatase activity in dopaminergic cells[J]. ACS Medicinal Chemistry Letters, 2014, 5 (7) : 782-786.