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1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite

Product Specifications

UNSPSC Description

1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

Target Antigen

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-2-deoxy-5-o-dmt-2-fluoro-b-d-arabinofuranosyl-thymine-3-ce-phosphoramidite.html

Solubility

10 mM in DMSO

Smiles

O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]2F

Molecular Weight

762.80

References & Citations

[1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-154604/1-2-Deoxy-5-O-DMT-2-fluoro-b-D-arabinofuranosyl-thymine-3-CE-phosphoramidite-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-154604/

Clinical Information

No Development Reported

CAS Number

208193-48-0

Available Sizes

Curated Selection

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