1- (2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl) thymine 3'-CE phosphoramidite
1- (2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl) thymine 3'-CE phosphoramidite is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
Product Specifications
CAS Number
[208193-48-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/1-2-deoxy-5-o-dmt-2-fluoro-b-d-arabinofuranosyl-thymine-3-ce-phosphoramidite.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C(C)=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H]2F
Molecular Formula
C40H48FN4O8P
Molecular Weight
762.80
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16 (9) :7980-93.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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