(+) -Mepivacaine

(+) -Mepivacaine is a racemic isomer of Mepivacaine (HY-B0517), which has analgesic and vasoconstrictive activity. Mepivacaine is an amide type agent that temporarily causes local loss of consciousness. Mepivacaine binds to specific voltage-gated sodium channels on neuronal cell membranes, inhibiting sodium influx and membrane depolarization[1].

Product Specifications

CAS Number

[24358-84-7]

Product Name Alternative

Dexivacaine; (S) -Mepivacaine

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/plus-mepivacaine.html

Purity

98.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=C(C=CC=C1C)C)[C@H]2N(CCCC2)C

Molecular Formula

C15H22N2O

Molecular Weight

246.35

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Fairley J W, et al. An intradermal study of the local anaesthetic and vascular effects of the isomers of mepivacaine[J]. British Journal of Anaesthesia, 1981, 53 (11) : 1211-1216.