BIBX 1382 (dihydrochloride)

BIBX 1382 dihydrochloride is an ErbB kinase inhibitor with significant antiviral activity. BIBX 1382 affects the ability of viruses to enter host cells by inhibiting members of the ErbB kinase family. It can be used to study the interaction mechanism between virus and host and the broad spectrum intervention of highly pathogenic viruses[1].

Product Specifications

CAS Number

[1216920-18-1]

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bibx-1382-dihydrochloride.html

Smiles

CN(CC1)CCC1NC2=NC(C(NC3=CC(Cl)=C(F)C=C3)=NC=N4)=C4C=N2.Cl.Cl

Molecular Formula

C18H21Cl3FN7

Molecular Weight

460.76

References & Citations

[1]Mohr E L, et al. Inhibitors of cellular kinases with broad-spectrum antiviral activity for hemorrhagic fever viruses[J]. Antiviral research, 2015, 120: 40-47.