BIBX 1382 (dihydrochloride)
BIBX 1382 dihydrochloride is an ErbB kinase inhibitor with significant antiviral activity. BIBX 1382 affects the ability of viruses to enter host cells by inhibiting members of the ErbB kinase family. It can be used to study the interaction mechanism between virus and host and the broad spectrum intervention of highly pathogenic viruses[1].
Product Specifications
CAS Number
[1216920-18-1]
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/bibx-1382-dihydrochloride.html
Smiles
CN(CC1)CCC1NC2=NC(C(NC3=CC(Cl)=C(F)C=C3)=NC=N4)=C4C=N2.Cl.Cl
Molecular Formula
C18H21Cl3FN7
Molecular Weight
460.76
References & Citations
[1]Mohr E L, et al. Inhibitors of cellular kinases with broad-spectrum antiviral activity for hemorrhagic fever viruses[J]. Antiviral research, 2015, 120: 40-47.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Curated Selection
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