Tylophorine
Tylophorine and its analogs are benzoindole alkaloids, most of which are derived from Garcinia plants. Tylophorine analogs all show potent growth inhibition against human hepatocellular carcinoma HepG2 and human nasopharyngeal carcinoma KB cell lines. Tylophorine analogs can also induce increased albumin expression and inhibit α-fetoprotein expression in HepG2 cells, and have the potential to induce HepG2 cell differentiation[1].
Product Specifications
CAS Number
[482-20-2]
Product Name Alternative
(+) - (S) -Tylophorine; DCB-3500; NSC-717335
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tylophorine.html
Purity
96.0
Solubility
DMSO : 44.46 mg/mL (ultrasonic;warming)
Smiles
COC1=C(C=C2C3=CC(OC)=C(C=C3C4=C(C2=C1)CN5[C@]([H])(C4)CCC5)OC)OC
Molecular Formula
C24H27NO4
Molecular Weight
393.48
References & Citations
[1]Novel Mode of Action of Tylophorine Analogs as Antitumor Compounds
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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