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Teclistamab

Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell lysis. Teclistamab can be used in studies of diseases related to multiple myeloma (MM) [1].

Product Specifications

CAS Number

2119595-80-9

Product Name Alternative

JNJ-7957; JNJ-64007957; Tecvayli

UNSPSC

12352203

Target

CD3

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/teclistamab.html

Purity

99.95

Solubility

10 mM in DMSO

Smiles

[Teclistamab]

Molecular Weight

(143.64 kDa)

References & Citations

[1]Kodandaram Pillarisetti, et al. Teclistamab is an active T cell-redirecting bispecific antibody against B-cell maturation antigen for multiple myeloma. Blood Adv. 2020 Sep 22;4 (18) :4538-4549.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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