PE/Elab Fluor® 594 Anti-Mouse CD8a Antibody[2.43]
Product Specifications
Background
CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α (CD8a) /β (CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.
Abbreviation
CD8a
Gene ID
12525
UniProt
P01731
Host
Rat
Reactivity
Mouse
Target
T8; Lyt2; Ly-2
Clonality
Monoclonal
Clone
2.43
Conjugation
PE/Elab Fluor®594
Applications
FCM
Concentration
5 μL/Test
Buffer
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Shipping Conditions
Ice bag
Storage Conditions
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Product Datasheet
https://789.bio/ea/zd4vml
Product MSDS
https://789.bio/eb/mSZyH4
Recommended Usage
The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .
Isotype
Rat IgG2b, κ
Available Sizes
Curated Selection
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