Taraxasteryl acetate

Taraxasteryl acetate is isolated from P. sagittalis, and has a broad spectrum of anti-inflammatory activity. Taraxasterol acetate promotes RNF31 degradation by activating autophagy. Taraxasteryl acetate relieves dextran, zymosan and arachidonic acid induced rat hind-paw edema. Taraxasteryl acetate can be used for the topical inflammation treatment[1][2].

Product Specifications

CAS Number

[6426-43-3]

UNSPSC

12352211

Target

Autophagy; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/taraxasteryl-acetate.html

Purity

98.74

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@@H](OC(C)=O)CC4)C)([H])CC2)C)([H])[C@]([C@@H]5C)([H])[C@](C)(CCC5=C)CC3)C

Molecular Formula

C32H52O2

Molecular Weight

468.75

References & Citations

[1]Pérez-García F, et al. Activity of taraxasteryl acetate on inflammation and heat shock protein synthesis.Phytomedicine. 2005 Apr;12 (4) :278-84.|[2]Chao-Tao Tang, et al. Taraxasterol acetate targets RNF31 to inhibit RNF31/p53 axis-driven cell proliferation in colorectal cancer. Cell Death Discov. 2021 Apr 6;7 (1) :66.