Chromomycin A2

Chromomycin A2 (Aburamycin A) has cytotoxicity and induces autophagy. Chromomycin A2 has anti-tumor activity and can be used in cancer research[1].

Product Specifications

CAS Number

[6992-70-7]

Product Name Alternative

Aburamycin A

UNSPSC

12352005

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/chromomycin-a2.html

Solubility

10 mM in DMSO

Smiles

O=C1C(C(C[C@]([C@H](OC)C([C@@H](O)[C@H](O)C)=O)([H])[C@@H]1O[C@@]2([H])C[C@H]([C@H](O)[C@@H](C)O2)O[C@@]3([H])C[C@H]([C@H](O)[C@@H](C)O3)O[C@@]4([H])C[C@](O)([C@@H](OC(C(C)C)=O)[C@H](C)O4)C)=CC5=CC(O[C@H]6C[C@H]([C@@H](OC(C)=O)[C@@H](C)O6)O[C@]7([H])C[C@H]([C@@H](OC)[C@@H](C)O7)O)=C8C)=C(O)C5=C8O

Molecular Formula

C59H86O26

Molecular Weight

1211.30

References & Citations

[1]Ratovitski EA. Tumor Protein (TP) -p53 Members as Regulators of Autophagy in Tumor Cells upon Marine Drug Exposure. Mar Drugs. 2016 Aug 16;14 (8) :154.