Guajadial
Guajadial, a caryophyllene-based meroterpenoid, has anti-estrogenic and anticancer effect. Guajadial reverses multidrug resistance in cancer. Guajadial can be isolated from Psidium guajava leaves[1][2].
Product Specifications
CAS Number
959860-49-2
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/guajadial.html
Solubility
10 mM in DMSO
Smiles
OC(C(C=O)=C1O)=C(C(O2)=C1C=O)[C@H](C3=CC=CC=C3)[C@](CCC4=C)([H])[C@@]2(CC[C@@]5([H])[C@@]4([H])CC(C)5C)C
Molecular Formula
C30H34O5
Molecular Weight
474.59
References & Citations
[1]Bazioli JM, et al. Anti-Estrogenic Activity of Guajadial Fraction, from Guava Leaves (Psidium guajava L.) . Molecules. 2020 Mar 27;25 (7) :1525.|[2]Li Y, et al. Guajadial reverses multidrug resistance by inhibiting ABC transporter expression and suppressing the PI3K/Akt pathway in drug-resistant breast cancer cells. Chem Biol Interact. 2019 May 25;305:98-104.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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