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PIP5K1α-IN-1

PIP5K1α-IN-1 (Compound 3e) is an inhibitor for phosphatidylinositol 4-phosphate 5-kinase type I α (PIP5K1α) with an IC50 of 0.46 μM[1].

Product Specifications

CAS Number

[3063813-76-0]

UNSPSC

12352005

Target

PI4P5K

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pip5k1α-in-1.html

Purity

99.81

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C1=C(C=CC2=C1CC[C@@]3([H])C(C)(CCC[C@]23C)C)OCC4=CN(N=N4)C5=CC([N+]([O-])=O)=CC=C5)C

Molecular Formula

C29H36N4O3

Molecular Weight

488.62

References & Citations

[1]Haidar S, et al. “1,2,3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors.” Bioorganic & medicinal chemistry vol. 105 (2024) : 117727.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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