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BRD4097

BRD4097 is an inhibitor of histone deacetylase (HDAC) . BRD4097 acts by inhibiting the activity of HDACs, especially HDAC 1,2 and 3, through metal chelation and spatial rejection mechanisms, and this inhibition may help regulate gene expression and alter chromatin structure, thereby affecting a variety of biological processes. BRD4097 is used to study the role of HDAC in cholesterol metabolism and NPC1 diseases[1].

Product Specifications

CAS Number

[1550053-19-4]

UNSPSC

12352005

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/brd4097.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(NC(C)=O)C=C1)NC2=CC=C(C)C=C2N

Molecular Formula

C16H17N3O2

Molecular Weight

283.33

References & Citations

[1]Cruz D L, et al. Inhibition of histone deacetylases 1, 2, and 3 enhances clearance of cholesterol accumulation in Niemann-Pick C1 fibroblasts[J]. ACS Pharmacology & Translational Science, 2021, 4 (3) : 1136-1148.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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