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Cpn10 Antibody (Biotin)

Rabbit polyclonal to Cpn10 (Biotin) . Chaperonin 10, otherwise known as Cpn10, (groES in E. coli) make up a family of small heart shock proteins with an approximate molecular mass of 10kDa (Hsp10s) . Cpn10 acts as a co-chaperone and interacts with the Hsp60 family to promote proper folding of polypeptides. Cpn10 and Cpn60 both exhibit sevenfold axis of symmetry and function as a team in the protein folding and assembly process. Cpn10 has been located in human platelets, but is also present in human maternal serum. It has been reported that human Cpn10 is identical with early pregnancy factor, which is involved in control over cell growth and development. This identification suggest that Cpn10 may act like a hormone in stressful situations such as pregnancy..

Product Specifications

Product Name Alternative

10kDa Chaperonin, Chaperonin 10, Cpn 10, EPF, GROES, Heat Shock 10kD protein1, HSP10, HSPE1

UniProt

P61604

Reactivity

Bovine, Canine, Frog, Guinea pig, Human, Mouse, Porcine, Rabbit, Rat, Sheep

Immunogen

Human Cpn10 peptide AA 91-101

Target

Cpn10

Clonality

Polyclonal

Conjugation

Biotin

Field of Research

Cancer Biology, Cell Biology, Metabolism Research, Protein Biochemistry, Signal Transduction

Purification

Protein A Purified

Concentration

1 mg/ml

Dilution

WB (1:1000), IHC (1:100)

Molecular Weight

10kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

1 μg/ml was sufficient for detection of Cpn10 in 10 μg of Hela lysates by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Tested Applications

ELISA, ICC, IF, IHC, IP, WB

NCBI Accession Number

NP_002148.1

Host or Source

Rabbit

Preservative

136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate.

Entrez

3336

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