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CDC37 Antibody (Biotin)

Rabbit polyclonal to CDC37 (Biotin) . Hsp90 co-chaperone Cdc37 is a protein that is encoded by the CDC37 gene. It has been found to form complexes with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK and elF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multi-targeted therapies.

Product Specifications

Product Name Alternative

CDC37, Hsp90 co-chaperone Cdc37, Cell division control protein 37, Hsp90 chaperone protein kinase-targeting subunit, CDC37_HUMAN, CDC37A, p50, p50Cdc37, S. cerevisiae hypothetical protein CDC37

UniProt

Q16543

Reactivity

Human

Immunogen

Native human Cdc37, full length

Target

CDC37

Clonality

Polyclonal

Conjugation

Biotin

Field of Research

Cancer Biology, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Purification

Protein A Purified

Concentration

1.68 mg/ml

Dilution

WB (1:2000), ICC/IF (1:200)

Molecular Weight

44.5kDa

Storage Conditions

Conjugated antibodies should be stored according to the product label

Notes

For research use only.

Applications Notes

A 1:2000 dilution was sufficient for detection of cdc37 in 20 μg of HeLa cell lysate by ECL immunoblot analysis.

Tested Applications

ICC, IF, IHC

NCBI Accession Number

NP_008996.1

Host or Source

Rabbit

Preservative

136.36mM Ethanolamine, 133.23 mM Chlorides, 9.55mM Phosphates, 9.55mM Sodium Bicarbonate.

Entrez

11140

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