Lupulone (Standard)

Lupulone (Standard) is the analytical standard of Lupulone. This product is intended for research and analytical applications. Lupulone is a beta-acid from the hop plant H. lupulus with diverse biological activities including antibacterial, antioxidant, and anticarcinogenic properties[1][2][3].

Product Specifications

CAS Number

[468-28-0]

UNSPSC

12352211

Target

Bacterial; Reference Standards

Type

Reference compound

Related Pathways

Anti-infection; Others

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/lupulone-standard.html

Smiles

O=C1C(C/C=C(C)\C)=C(C(C(CC(C)C)=O)=C(C1(C/C=C(C)\C)C/C=C(C)\C)O)O

Molecular Formula

C26H38O4

Molecular Weight

414.58

References & Citations

[1]Tagashira M, et al. Antioxidative activity of hop bitter acids and their analogues. Biosci Biotechnol Biochem. 1995 Apr;59 (4) :740-2. |[2]Lamy V, et al. Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells. Apoptosis 13 (10), 1232-1242 (2008) .|[3]Bocquet L, et al. Phenolic Compounds from Humulus lupulus as Natural Antimicrobial Products: New Weapons in the Fight against Methicillin Resistant Staphylococcus aureus, Leishmania mexicana and Trypanosoma brucei Strains. Molecules. 2019 Mar 14;24 (6) :1024. |[4]Tagashira M, et al. Antioxidative activity of hop bitter acids and their analogues. Biosci Biotechnol Biochem. 1995 Apr;59 (4) :740-2. |[5]Lamy V, et al. Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells. Apoptosis 13 (10), 1232-1242 (2008) .|[6]Bocquet L, et al. Phenolic Compounds from Humulus lupulus as Natural Antimicrobial Products: New Weapons in the Fight against Methicillin Resistant Staphylococcus aureus, Leishmania mexicana and Trypanosoma brucei Strains. Molecules. 2019 Mar 14;24 (6) :1024.