Dasantafil
Dasantafil (SCH-446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to in genitourinary disorders and study erectile dysfunction[1].
Product Specifications
CAS Number
569351-91-3
Product Name Alternative
SCH-446132
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dasantafil.html
Purity
98.35
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OCCN(C(N(C1=O)CC)=O)C(N=C2N[C@H]3[C@@H](CCC3)O)=C1N2CC4=CC(Br)=C(C=C4)OC
Molecular Formula
C22H28BrN5O5
Molecular Weight
522.39
References & Citations
[1]Galo M, et al. Targeted therapy with phosphodiesterase 5 inhibitors in patients with pulmonary hypertension due to heart failure and elevated pulmonary vascular resistance: a systematic review. Pulm Circ. 2020 Jul-Sep; 10 (3) : 2045894020948780.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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