Dasantafil

Dasantafil (SCH-446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to in genitourinary disorders and study erectile dysfunction[1].

Product Specifications

CAS Number

[569351-91-3]

Product Name Alternative

SCH-446132

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dasantafil.html

Purity

98.35

Solubility

DMSO : ≥ 100 mg/mL

Smiles

OCCN(C(N(C1=O)CC)=O)C(N=C2N[C@H]3[C@@H](CCC3)O)=C1N2CC4=CC(Br)=C(C=C4)OC

Molecular Formula

C22H28BrN5O5

Molecular Weight

522.39

References & Citations

[1]Galo M, et al. Targeted therapy with phosphodiesterase 5 inhibitors in patients with pulmonary hypertension due to heart failure and elevated pulmonary vascular resistance: a systematic review. Pulm Circ. 2020 Jul-Sep; 10 (3) : 2045894020948780.