Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Hexa-D-arginine

Hexa-D-arginine (Furin Inhibitor II) is a stable furin inhibitor with Ki values 106 nM, 580 nM and 13.2 μM for furin, PACE4 and prohormone convertase-1 (PC1), respectively. Hexa-D-arginine blocks Pseudomonas exotoxin A and anthrax toxins toxicity in vitro and in vivo[1][2][3].

Product Specifications

CAS Number

673202-67-0

Product Name Alternative

Furin Inhibitor II

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Hexa-D-arginine.html

Purity

99.97

Solubility

DMSO : 5 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C([C@@H](CCCNC(N)=N)NC([C@@H](CCCNC(N)=N)NC([C@H](N)CCCNC(N)=N)=O)=O)N[C@H](CCCNC(N)=N)C(N[C@H](CCCNC(N)=N)C(N[C@@H](C(N)=O)CCCNC(N)=N)=O)=O

Molecular Formula

C36H75N25O6

Molecular Weight

954.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Sarac MS, et al. The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo. Infect Immun. 2002 Dec;70 (12) :7136-9.|[2]Sarac MS, et al. Protection against anthrax toxemia by hexa-D-arginine in vitro and in vivo. Infect Immun. 2004 Jan;72 (1) :602-5.|[3]Cameron A, et al. Polyarginines are potent furin inhibitors. J Biol Chem. 2000 Nov 24;275 (47) :36741-9.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Scfd1 Mouse Gene Knockout Kit (CRISPR)
KN515353 1 Kit

Scfd1 Mouse Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
P4HA2 (NM_001142598) Human Over-expression Lysate
LC428199 20 µg

P4HA2 (NM_001142598) Human Over-expression Lysate

Sign In for Pricing
View Details
Human NHLRC2 activation kit by CRISPRa
GA117759 1 Kit

Human NHLRC2 activation kit by CRISPRa

Sign In for Pricing
View Details
Hepatocyte Specific (CPS1/1022), CF488A conjugate, 0.1mg/mL
BNC881022-500 1x 500 µL

Hepatocyte Specific (CPS1/1022), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details
TFIP11 Rabbit Polyclonal Antibody
TA362854 100 µL

TFIP11 Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Dextran (Technical Grade~ 20K)
TRC-D299115-50G 50 g

Dextran (Technical Grade~ 20K)

Sign In for Pricing
View Details