Regaloside B

Regaloside B is a phenylpropane. Regaloside B can be isolated from Lilium longiflorum. Regaloside B can inhibit the expression of VCAM-1, iNOS, and COX-2, with a p-p65/p-65 ratio. Regaloside B inhibits the mRNA of various chemokines and angiogenic factors (CXCL9, CXCL10, IL8, IDO) . Regaloside B has anti-inflammatory activity. Regaloside B can be used for osteogenic differentiation research[1][2][3].

Product Specifications

CAS Number

[114420-67-6]

UNSPSC

12352005

Target

COX; CXCR; Indoleamine 2,3-Dioxygenase (IDO) ; Interleukin Related; NF-κB; NO Synthase

Type

Natural Products

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Endocrinology; Inflammation/Immunology; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/regaloside-b.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1O[C@H](COC(/C=C/C2=CC=C(O)C=C2)=O)COC(C)=O

Molecular Formula

C20H26O11

Molecular Weight

442.41

References & Citations

[1]Thi NN, et, al. Phenylpropanoids from Lilium Asiatic hybrid flowers and their anti-inflammatory activities. Applied Biological Chemistry. 2017; 60: 527–533.|[2]Kim BR, et, al. Purification of Phenylpropanoids from the Scaly Bulbs of Lilium Longiflorum by CPC and Determination of Their DPP-IV Inhibitory Potentials. ACS Omega. 2020 Feb 20; 5 (8) : 4050-4057.|[3]Chen G, et al. Total Glycosides and Regaloside B from Lily: Potential Therapeutic Agents for Osteogenic Differentiation, Migration, and Angiogenesis. ACS Omega. 2025 Jul 20;10 (29) :31638-31648.