NF-kB (Luc) Jurkat Reporter Cell
NF-kB (Luc) Jurkat Reporter Cell is expressed from Human Jurkat.
Product Specifications
Background
The nuclear factor-κB (NF-κB) transcription factor family, which has been considered the central mediator of the inflammatory process and a key participant in innate and adaptive immune responses, could accelerate cell proliferation, inhibit apoptosis, promote cell migration and invasion, and stimulate angiogenesis and metastasis. Notably, in many types of cancer, both in malignant cells and in the tumour microenvironment, NFκB is constitutively active. Most of the increased NF-κB activity observed in solid malignancies is due to elevated production of IKK activating cytokines, including tumour necrosis factor (TNF) and IL-1.
Host
Jurkat
Origin Species
Human
Target
NF-κB
Tag
Luc
Applications
• The discovery of activators or inhibitors by the NF-kB signaling bioactivity • Transfection host for some receptors concerning the NF-kB signaling pathway
Format
Liquid
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
Frozen in liquid nitrogen
Package Size
1Vial*2
Host or Source
Jurkat
Species
Human
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