Indocyanine green

Indocyanine green (Foxgreen) is a low toxicic fluorescent agent that has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography (Ex/Em = 785/813 nm) [1].

Product Specifications

CAS Number

[3599-32-4]

Product Name Alternative

Foxgreen; IC Green; Cardiogreen

UNSPSC

12171500

Hazard Statement

H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Cardiogreen.html

Purity

98.23

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(CCCC[N+]1=C(/C=C/C=C/C=C/C=C2N(CCCCS(=O)(O[Na])=O)C3=C(C4=CC=CC=C4C=C3)C/2(C)C)C(C)(C)C5=C1C=CC6=CC=CC=C56)([O-])=O

Molecular Formula

C43H47N2NaO6S2

Molecular Weight

774.96

Precautions

H315, H319, H335

References & Citations

[1]Gharesi S, et al. Effect of photodynamic therapy based on indocyanine green on expression of apoptosis-related genes in human gingival fibroblast cells. Photodiagnosis Photodyn Ther. 2017 Apr 21.|[2]Taylor JS, et al. Combined application of Indocyanine green (ICG) and laser lead to targeted tumor cell destruction. J Pediatr Surg. 2018;53 (12) :2475-2479.|[3]Mačianskienė R, et al. Spectral characteristics of voltage-sensitive indocyanine green fluorescence in the heart. Sci Rep. 2017;7 (1) :7983. Published 2017 Aug 11.