Topoisomerase IIα-IN-9
Topoisomerase IIα-IN-9 (NSC85582) is a bisphenol compound that has a moderate inhibitory effect on DNA topoisomerase Topoisomerase II (IC50: 571 μM) . Topoisomerase IIα-IN-9 also exhibits a certain cell growth inhibitory effect, with IC50s of 117 μM and 218 μM for K562 and CHO, respectively[1].
Product Specifications
CAS Number
[16346-97-7]
Product Name Alternative
4,4'-Sulfonylbis (2-methylphenol)
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-iiα-in-9.html
Smiles
OC1=CC=C(S(=O)(C2=CC=C(O)C(C)=C2)=O)C=C1C
Molecular Formula
C14H14O4S
Molecular Weight
278.32
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]A Three-Dimensional Quantitative Structure-Activity Analysis of a New Class of Bisphenol Topoisomerase II Inhibitors
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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