CRGDfK-thioacetyl ester (TFA)
CRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging[1][2].
Product Specifications
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/crgdfk-thioacetyl-ester-tfa.html
Purity
99.30
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CSC(C)=O)=O)[C@H]1CC2=CC=CC=C2.O=C(O)C(F)(F)F.[x]
Molecular Formula
C31H45N9O9S.xC2HF3O2
Molecular Weight
719.81 (free base)
References & Citations
[1]Toti US, et al. Interfacial activity assisted surface functionalization: a novel approach to incorporate maleimide functional groups and cRGD peptide on polymeric nanoparticles for targeted drug delivery. Mol Pharm. 2010 Aug 2;7 (4) :1108-17.|[2]Gamage RS, et al. Comparison of cRGDfK Peptide Probes with Appended Shielded Heptamethine Cyanine Dye (s775z) for Near Infrared Fluorescence Imaging of Cancer. ACS Omega. 2021 Oct 30;6 (44) :30130-30139.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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