11-Deoxy prostaglandin E1
11-Deoxy prostaglandin E1 (AY-23578; Doproston B) is an analog of prostaglandin E1 (PGE1) with bronchodilator activity. 11-Deoxy prostaglandin E1 inhibits histamine-induced bronchoconstriction and causes relaxation of tracheal strips in isolated guinea pigs[1].
Product Specifications
CAS Number
[37786-00-8]
Product Name Alternative
AY-23578; Doproston B; 11-Deoxy-PGE1
UNSPSC
12352211
Hazard Statement
H302-H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/11-deoxy-prostaglandin-e1.html
Solubility
10 mM in DMSO
Smiles
OC(CCCCCC[C@@H]1[C@H](CCC1=O)/C=C/[C@@H](O)CCCCC)=O
Molecular Formula
C20H34O4
Molecular Weight
338.48
Precautions
P264-P270-P280-P330-P405-P501
References & Citations
[1]Greenberg R, et al. The bronchodilator acitivity of an 11-deoxyprostaglandin (AY 23 578) . Can J Physiol Pharmacol. 1975 Oct;53 (5) :799-809.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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