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CSNK1-IN-2

CSNK1-IN-2 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 2.52 μM. CSNK1-IN-2 can be used for the research of proliferative disorders[1].

Product Specifications

CAS Number

2468783-76-6

UNSPSC

12352005

Target

Casein Kinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/csnk1-in-2.html

Purity

99.22

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N(CC1)C)C2=C1NC(C3=CC=NC(NC([C@@H](C4=CC=C(C=C4)F)C)=O)=C3)=C2NC5=CC=CC=C5

Molecular Formula

C28H26FN5O2

Molecular Weight

483.54

References & Citations

[1]Volker Schulze, et al. 3-amino-2-[2- (acylamino) pyridin-4-yl]-1,5,6,7-tetrahydro-4h-pyrrolo[3,2-c]pyridin-4-one as csnk1 inhibitors. Patent. WO2020161257 A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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