H-0106 (dihydrochloride)
H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP) -lowering activity. H-0106 dihydrochloride can effectively inhibit ROCK enzyme. H-0106 dihydrochloride demonstrated significant IOP-lowering effects in monkey eyes. Studies with H-0106 dihydrochloride suggest that there may not be a direct relationship between ROCK inhibition and IOP reduction[1].
Product Specifications
CAS Number
[1011465-90-9]
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-0106-dihydrochloride.html
Smiles
O=S(C1=CC=CC2=C1C(Cl)=CN=C2)(N3[C@H](CNCCCC3)C)=O.[H]Cl.[H]Cl
Molecular Formula
C16H22Cl3N3O2S
Molecular Weight
426.79
References & Citations
[1]IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Gm2016 (NM_001122662) Mouse Tagged ORF Clone Lentiviral Particle
