H-0106 (dihydrochloride)
Product Specifications
UNSPSC Description
H-0106 dihydrochloride is a ROCK inhibitor with potent intraocular pressure (IOP)-lowering activity. H-0106 dihydrochloride can effectively inhibit ROCK enzyme. H-0106 dihydrochloride demonstrated significant IOP-lowering effects in monkey eyes. Studies with H-0106 dihydrochloride suggest that there may not be a direct relationship between ROCK inhibition and IOP reduction[1].
Target Antigen
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/h-0106-dihydrochloride.html
Smiles
O=S(C1=CC=CC2=C1C(Cl)=CN=C2)(N3[C@H](CNCCCC3)C)=O.[H]Cl.[H]Cl
Molecular Weight
426.79
References & Citations
[1]IOP-lowering effect of isoquinoline-5-sulfonamide compounds in ocular normotensive monkeys
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-113600/H-0106-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-113600/
Clinical Information
No Development Reported
CAS Number
1011465-90-9
Curated Selection
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