Recombinant MAP2K1 (MEK1) Protein

<strong>Recombinant MAP2K1 (MEK1) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017587_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 46.8 kDa_x000D_ <strong>Supplied as:</strong> SOLUTION_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Mitogen-Activated Protein Kinase Kinase 1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yamamoto T, Tsigelny IF, Götz AW, Howell SB. Cisplatin inhibits MEK1/2 Oncotarget. 2015 Sep 15;6(27):23510-22._x000D_ 2: Oza JP, Aerni HR, Pirman NL, Barber KW, Ter Haar CM, Rogulina S, Amrofell MB, Isaacs FJ, Rinehart J, Jewett MC. Robust production of recombinant phosphoproteins using cell-free protein synthesis Nat Commun. 2015 Sep 9;6:8168._x000D_ 3: Yun MW, Kim K, Park JY, Chung KY. Conformational Dynamics Analysis of MEK1 Using Hydrogen/Deuterium Exchange Mass Spectrometry Protein Pept Lett. 2021;28(5):481-488._x000D_ 4: Gillespie-Brown J, Fuller SJ, Bogoyevitch MA, Cowley S, Sugden PH. The mitogen-activated protein kinase kinase MEK1 stimulates a pattern of gene expression typical of the hypertrophic phenotype in rat ventricular cardiomyocytes J Biol Chem. 1995 Nov 24;270(47):28092-6._x000D_ 5: Hirata H, Hinoda Y, Ueno K, Shahryari V, Tabatabai ZL, Dahiya R. MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer Carcinogenesis. 2012 Jan;33(1):41-8._x000D_ 6: Pham CD, Arlinghaus RB, Zheng CF, Guan KL, Singh B. Characterization of MEK1 phosphorylation by the v-Mos protein Oncogene. 1995 Apr 20;10(8):1683-8._x000D_ 7: Russell M, Lange-Carter CA, Johnson GL. Regulation of recombinant MEK1 and MEK2b expressed in Escherichia coli Biochemistry. 1995 May 23;34(20):6611-5._x000D_ 8: Huang CY, Chou YH, Hsieh NT, Chen HH, Lee MF. MED28 regulates MEK1-dependent cellular migration in human breast cancer cells J Cell Physiol. 2012 Dec;227(12):3820-7._x000D_ 9: Fleischmann J, Feichtner A, DeFalco L, Kugler V, Schwaighofer S, Huber RG, Stefan E. Allosteric Kinase Inhibitors Reshape MEK1 Kinase Activity Conformations in Cells and In Silico Biomolecules. 2021 Mar 30;11(4):518._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/22327936">10: Choi YL, Soda M, Ueno T, Hamada T, Haruta H, Yamato A, Fukumura K, Ando M, Kawazu M, Yamashita Y, Mano H. Oncogenic MAP2K1 mutations in human epithelial tumors Carcinogenesis. 2012 May;33(5):956-61. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant MAP2K1 (MEK1) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>