T-2 Triol

T-2 Triol is a trichothecene mycotoxin derived by the metabolism of T-2 toxin. It is less toxic than T-2 toxin[1]. T-2 Triol major metabolites are evaluated in broiler chickens with Half-lives (t1/2λz), Peak plasma concentrations (Cmax) and Tmax values of 9.6 mins, 563 ng/ml , 2.5 mins, respectively[2].

Product Specifications

CAS Number

[34114-98-2]

UNSPSC

12352005

Hazard Statement

H225-H302+H312+H332-H319

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/t2-toxin-triol.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@H](O)[C@@H](O)[C@H]([C@@]23CO3)O[C@]4([H])C=C(C)[C@@H](OC(CC(C)C)=O)C[C@]14CO

Molecular Formula

C20H30O7

Molecular Weight

382.45

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P362+P364-P370+P378-P403+P235-P501

References & Citations

[1]Li Y, et al. T-2 toxin, a trichothecene mycotoxin: review of toxicity, metabolism, and analytical methods. J Agric Food Chem. 2011 Apr 27;59 (8) :3441-53.|[2]Sun YX, et al. Toxicokinetics of T-2 toxin and its major metabolites in broiler chickens after intravenous and oral administration. J Vet Pharmacol Ther. 2015 Feb;38 (1) :80-5.