DNA Methyltransferase Inhibitor

<strong>DNA Methyltransferase Inhibitor</strong>_x000D_ <strong>Catalog number:</strong> B2012767_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 334.3 g/mol_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> DNA Methyltransferase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Stresemann C, Lyko F. Modes of action of the DNA methyltransferase inhibitors azacytidine and decitabine Int J Cancer. 2008 Jul 1;123(1):8-13._x000D_ 2: Lu CH, Chen CM, Ma J, Wu CJ, Chen LC, Kuo ML. DNA methyltransferase inhibitor alleviates bleomycin-induced pulmonary inflammation Int Immunopharmacol. 2020 Jul;84:106542._x000D_ 3: Hu C, Liu X, Zeng Y, Liu J, Wu F. DNA methyltransferase inhibitors combination therapy for the treatment of solid tumor: mechanism and clinical application Clin Epigenetics. 2021 Aug 27;13(1):166._x000D_ 4: Li J, Liang Y, Fan J, Xu C, Guan B, Zhang J, Guo B, Shi Y, Wang P, Tan Y, Zhang Q, Yuan C, Wu Y, Zhou L, Ci W, Li X. DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma BMC Med. 2022 Jul 18;20(1):222._x000D_ 5: Ma F, Zhang Q, Zhang CY. Nanomaterial-based biosensors for DNA methyltransferase assay J Mater Chem B. 2020 Apr 29;8(16):3488-3501._x000D_ 6: Wu S, Li X, Gao F, de Groot JF, Koul D, Yung WKA. PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma Neuro Oncol. 2021 Jun 1;23(6):920-931._x000D_ 7: Zhou Z, Li HQ, Liu F. DNA Methyltransferase Inhibitors and their Therapeutic Potential Curr Top Med Chem. 2018;18(28):2448-2457._x000D_ 8: Zhang J, Stevens MF, Bradshaw TD. Temozolomide: mechanisms of action, repair and resistance Curr Mol Pharmacol. 2012 Jan;5(1):102-14._x000D_ 9: Chen Z, Jin G, Lin S, Lin X, Gu Y, Zhu Y, Hu C, Zhang Q, Wu L, Shen H. DNA methyltransferase inhibitor CDA-II inhibits myogenic differentiation Biochem Biophys Res Commun. 2012 Jun 8;422(3):522-6._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/27002722">10: Harman RM, Curtis TM, Argyle DJ, Coonrod SA, Van de Walle GR. A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species J Mammary Gland Biol Neoplasia. 2016 Jun;21(1-2):51-66. </a>_x000D_ _x000D_ <strong>Products Related to DNA Methyltransferase Inhibitor can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>