COX-2-IN-46
COX-2-IN-46 (compound 5m) is an anti-inflammatory agent with potent analgesic activity. COX-2-IN-46 exhibits a significant inhibitory effect on COX-2 (IC50=87.74 nM) [1].
Product Specifications
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-46.html
Smiles
FC1=CC=C(C2CC(C3=CC=C4C=CC=CC4=C3)=NN2C5=NC(C6=CC=C(F)C=C6)=CS5)C=C1
Molecular Formula
C28H19F2N3S
Molecular Weight
467.53
References & Citations
[1]Mohammed, et al. "Discovery of new 2- (3- (naphthalen-2-yl) -4, 5-dihydro-1H-pyrazol-1-yl) thiazole derivatives with potential analgesic and anti-inflammatory activities: In vitro, in vivo and in silico investigations." Bioorganic Chemistry 147 (2024) : 107372.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-2
Frequently Asked Questions
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