D-JBD19

D-JBD19 is an impermeable peptide that serves as an inactive control for the JNK inhibitor D-JNKI1 (HY-P0069) . D-JNKI1 has neuroprotective effects[1][2].

Product Specifications

CAS Number

[954134-42-0]

UNSPSC

12352209

Target

JNK

Type

Peptides

Related Pathways

MAPK/ERK Pathway

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/d-jbd19.html

Purity

99.84

Solubility

10 mM in DMSO

Smiles

N=C(N)NCCC[C@H](C(O)=O)NC([C@@H]1N(C([C@@H](CCCCN)NC([C@@H](CCCNC(N)=N)NC([C@@H]2N(C([C@@H]([C@@H](O)C)NC([C@@H]([C@@H](O)C)NC([C@@H](CC(C)C)NC([C@@H](CC(N)=O)NC([C@@H](CC(C)C)NC([C@@H](CC3=CC=CC=C3)NC([C@@H]4N(C([C@@H](CCC(N)=O)NC([C@@H](C(C)C)NC([C@@H]5N(C([C@@H](CCCNC(N)=N)NC([C@@H](CO)NC([C@@H](CCC(N)=O)NC([C@@H](CC(O)=O)N)=O)=O)=O)=O)CCC5)=O)=O)=O)CCC4)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)=O)=O)CCC1)=O

Molecular Formula

C99H164N32O28

Molecular Weight

2250.56

References & Citations

[1]Cardozo AK, et al. Cell-permeable peptides induce dose- and length-dependent cytotoxic effects. Biochim Biophys Acta. 2007 Sep;1768 (9) :2222-34.|[2]Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119 (6) :1243-52.|[3]Vaslin A, et al. Excitotoxicity-induced endocytosis mediates neuroprotection by TAT-peptide-linked JNK inhibitor. J Neurochem. 2011 Dec;119 (6) :1243-52.