Chloroquinoxaline sulfonamide
Product Specifications
UNSPSC Description
Chloroquinoxaline sulfonamide (Chloroquinoxaline), a structural analogue of sulfaquinoxaline, is a topoisomerase II alpha/beta poison. Chloroquinoxaline sulfonamide is used to control coccidiosis in poultry, rabbit, sheep, and cattle[1]. Antitumor activity[2].
Target Antigen
Molecular Glues; Parasite; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection;Cell Cycle/DNA Damage;PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/chloroquinoxaline-sulfonamide.html
Purity
99.06
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC1=CC=CC2=NC(NS(=O)(C3=CC=C(N)C=C3)=O)=CN=C12
Molecular Weight
334.78
References & Citations
[1]Gao H, et al. Chloroquinoxaline sulfonamide (NSC 339004) is a topoisomerase IIalpha/beta poison. Cancer Res. 2000 Nov 1;60(21):5937-40.|[2]Branda RF, et al. Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. Biochem Pharmacol. 1988 Dec 1;37(23):4557-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106662/Chloroquinoxaline-sulfonamide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106662/Chloroquinoxaline-sulfonamide-SDS-MedChemExpress.pdf
Clinical Information
Phase 2
CAS Number
97919-22-7
Available Sizes
Curated Selection
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