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CD81 Monoclonal Antibody

<strong>CD81 Monoclonal Antibody</strong>_x000D_ <strong>Catalog number:</strong> B2015275_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 26 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> CD81, CD81 antigen, CD81 molecule, Cell and organelle markers, Exosome marker, S5.7, TAPA1, Tetraspanin 28, Tspan 28, TSPAN28_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Marabelle A, Le DT, Ascierto PA, Di Giacomo AM, De Jesus-Acosta A, Delord JP, Geva R, Gottfried M, Penel N, Hansen AR, Piha-Paul SA, Doi T, Gao B, Chung HC, Lopez-Martin J, Bang YJ, Frommer RS, Shah M, Ghori R, Joe AK, Pruitt SK, Diaz LA Jr. Efficacy of Pembrolizumab in Patients With Noncolorectal High Microsatellite Instability/Mismatch Repair-Deficient Cancer: Results From the Phase II KEYNOTE-158 Study J Clin Oncol. 2020 Jan 1;38(1):1-10._x000D_ 2: Hasezaki T, Yoshima T, Mattsson M, Särnefält A, Takubo K. A monoclonal antibody recognizing a new epitope on CD81 inhibits T-cell migration without inducing cytokine production J Biochem. 2020 Apr 1;167(4):399-409._x000D_ 3: O'Malley DM, Bariani GM, Cassier PA, Marabelle A, Hansen AR, De Jesus Acosta A, Miller WH Jr, Safra T, Italiano A, Mileshkin L, Xu L, Jin F, Norwood K, Maio M. Pembrolizumab in Patients With Microsatellite Instability-High Advanced Endometrial Cancer: Results From the KEYNOTE-158 Study J Clin Oncol. 2022 Mar 1;40(7):752-761._x000D_ 4: Bailly C, Thuru X. Targeting of Tetraspanin CD81 with Monoclonal Antibodies and Small Molecules to Combat Cancers and Viral Diseases Cancers (Basel). 2023 Apr 6;15(7):2186._x000D_ 5: Pavlasova G, Mraz M. The regulation and function of CD20: an "enigma" of B-cell biology and targeted therapy Haematologica. 2020 Jun;105(6):1494-1506._x000D_ 6: Rouanne M, Adam J, Radulescu C, Letourneur D, Bredel D, Mouraud S, Goubet AG, Leduc M, Chen N, Tan TZ, Signolle N, Bigorgne A, Dussiot M, Tselikas L, Susini S, Danlos FX, Schneider AK, Chabanon R, Vacher S, Bièche I, Lebret T, Allory Y, Soria JC, Arpaia N, Kroemer G, Kepp O, Thiery JP, Zitvogel L, Marabelle A. BCG therapy downregulates HLA-I on malignant cells to subvert antitumor immune responses in bladder cancer J Clin Invest. 2022 Jun 15;132(12):e145666._x000D_ 7: Fofana I, Xiao F, Thumann C, Turek M, Zona L, Tawar RG, Grunert F, Thompson J, Zeisel MB, Baumert TF. A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission PLoS One. 2013 May 21;8(5):e64221._x000D_ 8: Vexler V, Yu L, Pamulapati C, Garrido R, Grimm HP, Sriraman P, Bohini S, Schraeml M, Singh U, Brandt M, Ries S, Ma H, Klumpp K, Ji C. Target-mediated drug disposition and prolonged liver accumulation of a novel humanized anti-CD81 monoclonal antibody in cynomolgus monkeys MAbs. 2013 Sep-Oct;5(5):776-86._x000D_ 9: Maecker HT, Todd SC, Kim EC, Levy S. Differential expression of murine CD81 highlighted by new anti-mouse CD81 monoclonal antibodies Hybridoma. 2000 Feb;19(1):15-22._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25417967">10: Ji C, Liu Y, Pamulapati C, Bohini S, Fertig G, Schraeml M, Rubas W, Brandt M, Ries S, Ma H, Klumpp K. Prevention of hepatitis C virus infection and spread in human liver chimeric mice by an anti-CD81 monoclonal antibody Hepatology. 2015 Apr;61(4):1136-44. </a>_x000D_ _x000D_ <strong>Products Related to CD81 Monoclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>

Product Specifications

CAS Number

9007-83-4

Short Description

Catalog Number: B2015275 (10 ug)

Weight

0.15

Length

2

Width

0.5

Height

0.5

Frequently Asked Questions

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