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Garvicin KS, GakA

Garvicin KS, GakA is a peptide at sizes of 34 amino acids to form bacteriocin garvicin KS (GarKS), with other 2 peptides, GakB, and GakC. Garvicin KS, GakA inhibits fibroblast viability and proliferation. Garvicin KS, GakA with GakB, is a potent combination with good peptide stability, antimicrobial efficacy, and fibroblast viability/proliferation effects. Garvicin KS peptides inhibit MSSA with MIC values in the order GakB >GakC >GakA[1].

Product Specifications

CAS Number

2098351-24-5

UNSPSC

12352209

Target

Bacterial

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/garvicin-ks-gaka.html

Solubility

10 mM in DMSO

Smiles

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CC=1C=2C(NC1)=CC=CC2)NC(CNC([C@@H](NC([C@H](CC=3C=4C(NC3)=CC=CC4)NC([C@@H](NC([C@@H](NC(CNC(CNC(CNC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@H](CCSC)N)=O)=O)C)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)CCCCN)=O)C)=O)=O)C)=O)CCCCN)=O)[C@H](CC)C)=O)C(C)C)=O)=O)CCCCN)=O)=O)[C@H](C)C)=O)CC(C)C)=O)=O)=O)=O)C)=O)CO)=O)=O)CC(C)C)=O)=O)=O)CC(N)=O)=O)C(C)C)=O)=O)CCC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C(N[C@@H](CCCCN)C(O)=O)=O)C=5C=6C(NC5)=CC=CC6

Molecular Formula

C161H259N43O39S

Molecular Weight

3453.11

References & Citations

[1]Thapa RK, et al. Preformulation studies on novel garvicin KS peptides for topical applications. Eur J Pharm Sci. 2020 Aug 1;151:105333.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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