Protriptyline (N-methyl-d3) (hydrochloride)
Protriptyline (N-methyl-d3) (hydrochloride) is the deuterium labeled Protriptyline hydrochloride. Protriptyline hydrochloride is a tricyclic antidepressant (TCA), specifically a secondary amine, for the treatment of depression and ADHD. Unique among the TCAs, protriptyline tends to be energizing instead of sedating, used for narcolepsy to achieve a wakefulness-promoting effect[1].
Product Specifications
CAS Number
1435934-21-6
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
C(CCNC([2H])([2H])[2H])C1C=2C(C=CC=3C1=CC=CC3)=CC=CC2.Cl
Molecular Formula
C19H19D3ClN
Molecular Weight
266.40
References & Citations
[1]Hudgel DW. Pharmacologic treatment of obstructive sleep apnea. J Lab Clin Med. 1995;126 (1) :13-18.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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