Azalanstat
Azalanstat is an imidazole-dioxolane derivate that is a lanosterol 14-α demethylase inhibitor. Azalanstat is also a HO-1 (IC50 = 5.5 µM) and HO-2 (IC50 = 24.5 µM) inhibitor[1].
Product Specifications
CAS Number
143393-27-5
Product Name Alternative
RS-21607
UNSPSC
12352005
Target
Cytochrome P450; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/azalanstat.html
Smiles
ClC(C=C1)=CC=C1CC[C@]2(O[C@@H](CO2)CSC3=CC=C(C=C3)N)CN4C=CN=C4
Molecular Formula
C22H24ClN3O2S
Molecular Weight
429.96
References & Citations
[1]Salerno L, et al. Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application. Eur J Med Chem. 2019 Apr 1;167:439-453.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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