CLK8
CLK8 is a potent and specific CLOCK inhibitor that can disrupt the interaction between CLOCK and BMAL1 and interfere with nuclear translocation of CLOCK. CLK8 can be used for the research of disorders associated with dampened circadian rhythms[1].
Product Specifications
CAS Number
[898920-65-5]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Cryptochrome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/clk8.html
Purity
98.06
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(COC1=C(C(C2=CC=CC=C2)=CC(O3)=O)C3=C(CCC(C)(C)O4)C4=C1)NC5=C(C(N)=O)C=CC=C5
Molecular Formula
C29H26N2O6
Molecular Weight
498.53
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148765/CLK8-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148765/CLK8-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
DMRT2 (Doublesex-and mab-3-Related Transcription Factor 2, Doublesex-like 2 Protein, DSXL-2, DMRT2, DSXL2) (AP)
DMRT2 (Doublesex-and mab-3-Related Transcription Factor 2, Doublesex-like 2 Protein, DSXL-2, DMRT2, DSXL2) (AP)
RING1 CRISPRa sgRNA lentivector (set of three targets)(Human)