ARN25062
ARN25062 (compound 27) is a CDC42/RHOJ inhibitor with antitumor activity. ARN25062 is a novel trisubstituted pyrimidine derivative[1].
Product Specifications
CAS Number
[3036492-85-7]
UNSPSC
12352005
Target
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/arn25062.html
Smiles
FC(F)(C1=CC(NC2=CC(C3=CC=CC=C3)=NC(C4CCNCC4)=N2)=CC=C1)F
Molecular Formula
C22H21F3N4
Molecular Weight
398.42
References & Citations
[1]Nicoletta Brindani, et al. Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer. J Med Chem. 2023 Apr 27;66 (8) :5981-6001.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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