7H-Dibenzo[c, g]carbazole
7H-Dibenzo[c, g]carbazole (DBC) is an azaarene with high lipophilicity. 7H-Dibenzo[c, g]carbazole has carcinogenic activity and induce DNA adducts in fish, DNA adducts, mutations in diploid human fibroblasts and micronuclei in human blood lymphocytes. 7H-Dibenzo[c, g]carbazole is activated by cytochrome P450 enzymes resulting mainly in the generation of phenolic metabolites[1].
Product Specifications
CAS Number
[194-59-2]
Product Name Alternative
DBC
UNSPSC
12352005
Hazard Statement
H302, H319, H351
Target
Cytochrome P450
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7h-dibenzo-c-g-carbazole.html
Purity
99.98
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
C12=C(C3=CC=CC=C3C=C2)C(C4=CC=CC=C4C=C5)=C5N1
Molecular Formula
C20H13N
Molecular Weight
267.32
Precautions
H302, H319, H351
References & Citations
[1]Gabelova A. 7H-Dibenzo[c, g]carbazole: Metabolic pathways and toxicity. Chem Biol Interact. 2020 May 25;323:109077.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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