Glucocorticoid receptor agonist-1
Glucocorticoid receptor agonist-1 is a potent glucocorticoid receptor agonist with an IC50 of 2.8 nM extracted from patent WO2017210471A1, compound 41[1].
Product Specifications
CAS Number
2166375-82-0
UNSPSC
12352005
Target
ADC Payload; Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glucocorticoid-receptor-agonist-1.html
Purity
99.80
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@@]5(C(CC4)=CC(C=C5)=O)C)([H])[C@H](C3)O)([H])C[C@@]1([H])O[C@](C6=CC=C(C=C6)CC7=CC(N)=CC=C7)([H])O2)C)=O
Molecular Formula
C35H39NO6
Molecular Weight
569.69
References & Citations
[1]Michael J. Mcpherson, et al. Glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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