Izorlisib
Izorlisib (CH5132799) is a selective class I PI3K inhibitor. Izorlisib inhibits class I PI3Ks, particularly PI3Kα, with an IC50 of 14 nM.
Product Specifications
CAS Number
[1007207-67-1]
Product Name Alternative
CH5132799
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/izorlisib.html
Purity
99.01
Solubility
DMSO : 4.55 mg/mL (ultrasonic)
Smiles
NC1=NC=C(C2=C3C(N(S(=O)(C)=O)CC3)=NC(N4CCOCC4)=N2)C=N1
Molecular Formula
C15H19N7O3S
Molecular Weight
377.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15466/Izorlisib-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15466/Izorlisib-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
PI3KC2β; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ
Available Sizes
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