D-Nonamannuronic acid

D-Nonamannuronic acid, an alginate oligomer, is produced by marine brown algae and by a limited range of Gram negative bacteria. D-Nonamannuronic acid can be used for the research of pain and vascular dementia[1][2][3][4].

Product Specifications

CAS Number

[862694-99-3]

UNSPSC

12352005

Target

Bacterial

Type

Natural Products

Related Pathways

Anti-infection

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/d-nonamannuronic-acid.html

Solubility

10 mM in DMSO

Smiles

OC([C@@H](O[C@H]1O[C@@H]([C@@H]([C@@H]2O)O)[C@H](O[C@H]2O[C@@H]([C@@H]([C@@H]3O)O)[C@H](O[C@H]3O[C@@H]([C@@H]([C@@H]4O)O)[C@H](O[C@H]4O[C@@H]([C@@H]([C@@H]5O)O)[C@H](O[C@H]5O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)[C@H]([C@@H]([C@@H]1O)O)O[C@@H]([C@H]([C@H]6O)O)O[C@@H]([C@H]6O[C@@H]([C@H]([C@H]7O)O)O[C@@H]([C@H]7O[C@@H]([C@H]([C@H]8O)O)O[C@@H]([C@H]8O[C@@H]([C@H]([C@H]9O)O)O[C@@H]([C@H]9O)C(O)=O)C(O)=O)C(O)=O)C(O)=O)=O

Molecular Formula

C54H74O55

Molecular Weight

1603.13

References & Citations

[1]Heyraud A, et, al. HPLC analysis of saturated or unsaturated oligoguluronates and oligomannuronates. Application to the determination of the action pattern of Haliotis tuberculata alginate lyase. Carbohydr Res. 1996 Sep 23; 291:115-26.|[2]Iwamoto M, et, al. Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells. FEBS Lett. 2005 Aug 15; 579 (20) : 4423-9.|[3]Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of pain. CN106344595A.|[4]Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of vascular dementia. CN106344593A.