BTA-9881

BTA-9881 (MEDI-564) is a RSV inhibitor, with an EC50: 48 nM, 59 nM and 160 nM for RSV A2, RSV Long, and RSV B1. BTA-9881 has favorable pharmacokinetics property[1].

Product Specifications

CAS Number

[1646857-24-0]

Product Name Alternative

MEDI-564

UNSPSC

12352005

Target

RSV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bta-9881.html

Smiles

O=C1N2[C@@](C3=CC=C(C=C3)Cl)(N(CC2)C(C4=CC=CN=C4)=O)C5=C1C=CN=C5

Molecular Formula

C21H15ClN4O2

Molecular Weight

390.82

References & Citations

[1]Bond S, et al. 1,2,3,9b-Tetrahydro-5H-imidazo[2,1-a]isoindol-5-ones as a new class of respiratory syncytial virus (RSV) fusion inhibitors. Part 2: identification of BTA9881 as a preclinical candidate. Bioorg Med Chem Lett. 2015 Feb 15;25 (4) :976-81.