SEN-1269
SEN-1269 is a potent Aβ aggregation inhibitor. SEN-1269 blocks Aβ (1-42) aggregation and protects neuronal cell lines exposed to Aβ (1-42) . SEN-1269 reduces the deficits in LTP and memory induced by Aβ oligomers. SEN-1269 can be used for the research of Alzheimer's disease[1].
Product Specifications
CAS Number
[956128-01-1]
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sen-1269.html
Smiles
OC1=CC=CC(NC2=NC=C(OC3=CC=CC(N(C)C)=C3)C=N2)=C1
Molecular Formula
C18H18N4O2
Molecular Weight
322.36
References & Citations
[1]Scopes DI, et al. Aβ oligomer toxicity inhibitor protects memory in models of synaptic toxicity. Br J Pharmacol. 2012 Sep;167 (2) :383-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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