Ferric citrate

Ferric citrate (Iron (III) citrate), an orally active iron supplement, is an efficacious phosphate binder. Ferric citratee can be used for iron deficiency anemia and chronic kidney disease (CKD) research[1][2].

Product Specifications

CAS Number

[3522-50-7]

Product Name Alternative

Iron (III) citrate; Zerenex

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ferric-citrate.html

Purity

98.0

Solubility

H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(CC(C([O-])=O)(O)CC([O-])=O)[O-].[Fe+3]

Molecular Formula

C6H5FeO7

Molecular Weight

244.94

Precautions

H302, H315, H319, H335

References & Citations

[1]Yuichi Baba, et al. Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2018 Mar 1;314 (3) :H659-H668.|[2]Julia B Lewis, et al. Ferric citrate controls phosphorus and delivers iron in patients on dialysis. J Am Soc Nephrol. 2015 Feb;26 (2) :493-503.|[3]Connor Francis, et al. Ferric citrate reduces fibroblast growth factor 23 levels and improves renal and cardiac function in a mouse model of chronic kidney disease. Kidney Int. 2019 Dec;96 (6) :1346-1358.