Erenapurstat
Erenapursta (E3330) is a direct, orally active and selective inhibitor of Ape-1 (apurinic/apyrimidinic endonuclease 1) /Ref-1 (redox factor-1) redox. Erenapursta is able to impair tumor growth and blocks the activity of NF-κB, AP-1, and HIF-1α in pancreatic cancer. Erenapursta shows anticancer activities[1][2][3][4][5].
Product Specifications
CAS Number
136164-66-4
Product Name Alternative
E3330; APX-3330
UNSPSC
12352211
Hazard Statement
H302, H411
Target
AP-1; DNA/RNA Synthesis; HIF/HIF Prolyl-Hydroxylase; NF-κB; Reactive Oxygen Species (ROS) ; VEGFR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/e3330.html
Purity
99.67
Solubility
DMSO : 120 mg/mL (ultrasonic)
Smiles
CCCCCCCCC/C(C(O)=O)=C\C1=C(C)C(C(OC)=C(OC)C1=O)=O
Molecular Formula
C21H30O6
Molecular Weight
378.46
Precautions
H302, H411
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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