LP17
LP17 (LQVTDSGLYRCVIYHPP) is a BBB-penetrable triggering receptor expressed on myeloid cells (TREM-1) inhibitory peptide. LP17 substantially alleviates ischemia-induced infarction and neuronal injury. LP17 can get access into brain and block TREM-1[1].
Product Specifications
CAS Number
887255-16-5
Product Name Alternative
LQVTDSGLYRCVIYHPP
UNSPSC
12352209
Target
Others
Type
Peptides
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/lqvtdsglyrcviyhpp.html
Purity
99.78
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; adjust pH to 7 with CH3COOH; heat to 37°C) |H2O : 35.71 mg/mL (adjust pH to 3 with CH3COOH)
Smiles
O=C(N1[C@@H](CCC1)C(O)=O)[C@H]2N(CCC2)C([C@@H](NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@H](C(C)C)NC([C@H](CS)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H](CC(C)C)NC(CNC([C@H](CO)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC([C@H](CCC(N)=O)NC([C@@H](N)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CC5=CN=CN5)=O
Molecular Formula
C89H137N23O25S
Molecular Weight
1961.24
References & Citations
[1]Pengfei Xu, et al. Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke. Cell Death Dis. 2019 Jul 19;10 (8) :555.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6231700-01 0.1 mL
ATP6V1D (V-type Proton ATPase Subunit D, V-ATPase Subunit D, V-ATPase 28kD Accessory Protein, Vacuolar Proton Pump Subunit D, ATP6M, VATD) (MaxLight 750)
Sign In for Pricing
View Details MBS6231700-02 5x 0.1 mL
ATP6V1D (V-type Proton ATPase Subunit D, V-ATPase Subunit D, V-ATPase 28kD Accessory Protein, Vacuolar Proton Pump Subunit D, ATP6M, VATD) (MaxLight 750)
Sign In for Pricing
View Details