Ac-RYYRWK-NH2
Product Specifications
UNSPSC Description
Ac-RYYRWK-NH2 is a potent and selective partial agonist for the nociceptin receptor (NOP), [3H]Ac-RYYRWK-NH2 binds to rat cortical membranes ORL1 with a Kd of 0.071 nM, but has no affinity for µ-, κ- or δ-opioid receptors[1].
Target Antigen
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ac-ryyrwk-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C([R][Y][Y][R][W](N)[K])C
Molecular Weight
1012.17
References & Citations
[1]C T Dooley, et al. Binding and in vitro activities of peptides with high affinity for the nociceptin/orphanin FQ receptor, ORL1.J Pharmacol Exp Ther. 1997 Nov;283(2):735-41.|[2]M Ho, et al, Characterization of the ORL(1) receptor on adrenergic nerves in the rat anococcygeus muscle. Br J Pharmacol. 2000 Sep;131(2):349-55.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P1316/Ac-RYYRWK-NH2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P1316/
Clinical Information
No Development Reported
CAS Number
200959-47-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
