Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

OPC-163493

OPC-163493 is an orally active and liver-targeted mitochondrial uncoupling agent. OPC-163493 reduces the production of mitochondrial Δψ and ROS. OPC-163493 has anti-diabetic and lipid-lowering effects. In addition, OPC-163493 has a protective effect on cardiovascular disease[1][2].

Product Specifications

CAS Number

1644467-84-4

UNSPSC

12352005

Target

Mitochondrial Metabolism; Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/opc-163493.html

Purity

99.34

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

N#CC1=C(C2=C(C)SC(C3=CC=C(C(F)(F)F)C=C3)=N2)N=NN1

Molecular Formula

C14H8F3N5S

Molecular Weight

335.31

References & Citations

[1]Kanemoto N, et al. Antidiabetic and cardiovascular beneficial effects of a liver-localized mitochondrial uncoupler. Nat Commun. 2019 May 15;10 (1) :2172.|[2]Inoue Y, et al. Preclinical safety profile of a liver-localized mitochondrial uncoupler: OPC-163493. EXCLI J. 2022 Jan 11;21:213-235.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tissue FFPE Sections, Breast
CS716694 5x 5 µm

Tissue FFPE Sections, Breast

Sign In for Pricing
View Details
Mouse Etohd2 activation kit by CRISPRa
GA201304 1 Kit

Mouse Etohd2 activation kit by CRISPRa

Sign In for Pricing
View Details
CD44 Mouse Monoclonal Antibody [Clone ID: Bu52]
AM01076PU-N 200 µg

CD44 Mouse Monoclonal Antibody [Clone ID: Bu52]

Sign In for Pricing
View Details
CSF2RA Polyclonal Antibody
E-AB-90599-01 60 µL

CSF2RA Polyclonal Antibody

Sign In for Pricing
View Details
CSF2RA Polyclonal Antibody
E-AB-90599-02 120 µL

CSF2RA Polyclonal Antibody

Sign In for Pricing
View Details
CSF2RA Polyclonal Antibody
E-AB-90599-03 200 µL

CSF2RA Polyclonal Antibody

Sign In for Pricing
View Details